Entry Detail


General Information

Database ID:exR0511058
RNA Name:AGPAT3
RNA Type:mRNA
Chromosome:chr21
Starnd:+
Coordinate:
Start Site(bp):43865223End Site(bp):43987592
External Links:ENSG00000160216



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TUBB
chr6
30720352
30725426
+
WDR54
chr2
74421678
74425755
+
RPLP1
chr15
69452814
69456205
+
CARD9
chr9
136361903
136373681
-
VAPB
chr20
58389229
58451101
+
IPO9
chr1
201829149
201884291
+
KCTD3
chr1
215567304
215621807
+
IMP3
chr15
75639085
75648706
-
CLN3
chr16
28474111
28495575
-
OSGEP
chr14
20446401
20455089
-
PPRC1
chr10
102132994
102150333
+
CKLF
chr16
66552563
66566251
+
PDIA4
chr7
149003062
149028662
-
RBM15
chr1
110338506
110346681
+
RPL27A
chr11
8682788
8714759
+
ANKRD28
chr3
15667236
15859771
-
HLA-B
chr6
31269491
31357188
-
BHLHE40
chr3
4979437
4985323
+
SQSTM1
chr5
179806398
179838078
+
RER1
chr1
2391775
2405442
+
LAMC1
chr1
183023420
183145592
+
RUNDC1
chr17
42980565
42993690
+
POMK
chr8
43093506
43123434
+
GON4L
chr1
155749662
155859400
-
ACAP3
chr1
1292390
1309609
-
DTNBP1
chr6
15522801
15663058
-
PIK3R2
chr19
18153163
18170532
+
ACIN1
chr14
23058564
23095614
-
AC007192.1
chr19
18153158
18178117
+
SPC24
chr19
11131520
11155808
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL049840.4
chr14
103694516
103695050
-
AC010326.4
chr19
57867038
57868172
-
AL355075.4
chr14
20343048
20343685
-
LINC00665
chr19
36313067
36331770
-
LINC01754
chr20
47391925
47412327
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.