Entry Detail


General Information

Database ID:exR0511059
RNA Name:AGPAT4
RNA Type:mRNA
Chromosome:chr6
Starnd:-
Coordinate:
Start Site(bp):161129967End Site(bp):161274061
External Links:ENSG00000026652



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CLIC1
chr6
31730581
31739763
-
TMEM237
chr2
201620184
201643570
-
EIF4G2
chr11
10797050
10808940
-
METAP1
chr4
98995659
99062809
+
TNFRSF13B
chr17
16929816
16972118
-
ILF2
chr1
153661788
153671028
-
SPAG16
chr2
213284379
214410501
+
FASN
chr17
82078338
82098294
-
DCK
chr4
70992538
71030914
+
RPL13
chr16
89560657
89566828
+
HEXIM1
chr17
45148502
45152101
+
DDB1
chr11
61299451
61342596
-
PRR14
chr16
30650717
30656440
+
RPS27A
chr2
55231903
55235853
+
SYMPK
chr19
45815410
45863194
-
SNRPD2
chr19
45687454
45692569
-
RALY
chr20
33993646
34108308
+
BSG
chr19
571277
583493
+
RFT1
chr3
53088483
53130453
-
LRRN1
chr3
3799431
3849834
+
HP1BP3
chr1
20740266
20787323
-
RTF1
chr15
41408408
41483563
+
PHLDA1
chr12
76025447
76033932
-
CLIP1
chr12
122271432
122422632
-
GART
chr21
33503931
33543491
-
TOMM22
chr22
38681957
38685421
+
CCDC102A
chr16
57512181
57536571
-
TXLNA
chr1
32179675
32198285
+
TMED9
chr5
177592203
177597242
+
YIF1B
chr19
38303558
38317273
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005394.2
chr19
28435388
28727680
-
AL353719.1
chr10
99621055
99621918
+
JAKMIP2-AS1
chr5
147559994
147662009
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.