Entry Detail


General Information

Database ID:exR0511060
RNA Name:AGPAT5
RNA Type:mRNA
Chromosome:chr8
Starnd:+
Coordinate:
Start Site(bp):6708642End Site(bp):6761503
External Links:ENSG00000155189



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MFSD14B
chr9
94374569
94461042
+
RPL18A
chr19
17859910
17864153
+
NCL
chr2
231453531
231483641
-
PFN1
chr17
4945652
4949061
-
GNA12
chr7
2728105
2844308
-
RPL14
chr3
40457292
40468587
+
MMP24OS
chr20
35201745
35278131
-
Z82206.1
chr22
39960397
39964718
+
PRKAB1
chr12
119667864
119681624
+
TMEM129
chr4
1715952
1721358
-
PIGL
chr17
16217191
16351797
+
ARAP1
chr11
72685069
72793599
-
MRPL30
chr2
99181152
99199561
+
ELP3
chr8
28089673
28191156
+
AC010422.3
chr19
12643831
12648397
-
EEF1G
chr11
62559596
62574086
-
SLC9A3
chr5
470456
524449
-
EIF2A
chr3
150546678
150586016
+
ARL6IP1
chr16
18791669
18801572
-
TMEM241
chr18
23197144
23437961
-
PKIG
chr20
44531785
44624247
+
ATF2
chr2
175072250
175168382
-
LENG8
chr19
54448887
54462037
+
TMEM248
chr7
66921225
66958551
+
FKBP4
chr12
2794970
2805423
+
TPT1
chr13
45333471
45341370
-
ELL
chr19
18442663
18522116
-
DPY19L1
chr7
34928876
35038271
-
CRYL1
chr13
20403666
20525873
-
RACK1
chr5
181236897
181248096
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010442.1
chr5
466124
473098
-
AC104461.1
chr1
200333193
200478669
+
AL022311.1
chr22
37876148
37895563
+
AC116565.1
chr4
577168
618076
+
ESRG
chr3
54632122
54639857
-
MALAT1
chr11
65497688
65506516
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.