Entry Detail


General Information

Database ID:exR0511061
RNA Name:AGPS
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):177392757End Site(bp):177559299
External Links:ENSG00000018510



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
C2orf81
chr2
74414176
74421591
-
ZDHHC8
chr22
20129456
20148007
+
HES1
chr3
194136148
194138732
+
AP2M1
chr3
184174689
184184091
+
NDUFB11
chrX
47142216
47145504
-
RPS3A
chr4
151099624
151104642
+
NUDT15
chr13
48037726
48047221
+
HMGCR
chr5
75336329
75362101
+
OXA1L
chr14
22766522
22773042
+
RPL27A
chr11
8682788
8714759
+
RAB7A
chr3
128726183
128814798
+
RSRC2
chr12
122503454
122527000
-
CDCA7
chr2
173354820
173368997
+
DMWD
chr19
45782947
45792845
-
NCOR2
chr12
124324415
124567589
-
PSMC6
chr14
52707178
52728590
+
ATF4
chr22
39519695
39522685
+
EIF4G3
chr1
20806292
21176888
-
RPS24
chr10
78033760
78056813
+
ANAPC4
chr4
25377213
25418498
+
KHSRP
chr19
6413348
6424794
-
PSMB7
chr9
124353465
124415444
-
TRAP1
chr16
3651639
3717553
-
NCAPD2
chr12
6493356
6531955
+
FEZF2
chr3
62369681
62374324
-
ENO1
chr1
8861000
8879190
-
GPR176
chr15
39799008
39920266
-
HSPA4
chr5
133052013
133106449
+
RPL12
chr9
127447674
127451406
-
PARP2
chr14
20343582
20357905
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL022311.1
chr22
37876148
37895563
+
AC138932.3
chr16
14909887
14911345
-
AP005263.1
chr18
9102736
9254346
+
LINC00910
chr17
43338741
43389199
-
LINC01641
chr1
227393554
227431035
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.