Entry Detail


General Information

Database ID:exR0511070
RNA Name:AGTRAP
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):11736084End Site(bp):11754802
External Links:ENSG00000177674



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
LDHA
chr11
18394560
18408425
+
STK4
chr20
44966479
45080021
+
ACPP
chr3
132317369
132368298
+
HOXB1
chr17
48528526
48531011
-
TMSB4X
chrX
12975110
12977227
+
PAFAH1B3
chr19
42297033
42303546
-
KDM3A
chr2
86440647
86492716
+
ICE1
chr5
5420664
5490220
+
CCDC88C
chr14
91271323
91417844
-
TUBA1C
chr12
49188736
49274603
+
POGK
chr1
166839447
166856344
+
NUCB1
chr19
48900312
48923372
+
RPL30
chr8
98024851
98046469
-
HSF1
chr8
144291591
144314720
+
PABPC3
chr13
25095868
25099254
+
PABPN1
chr14
23321289
23326185
+
KRT19
chr17
41523617
41528308
-
SLC2A13
chr12
39755025
40106089
-
UBE2T
chr1
202331657
202341980
-
XPC
chr3
14145147
14178783
-
FUS
chr16
31180110
31194871
+
TJAP1
chr6
43477523
43506556
+
MAD2L2
chr1
11674480
11691650
-
CNPY3
chr6
42929192
42939294
+
STAT5B
chr17
42199177
42276707
-
SCARB1
chr12
124776856
124882668
-
IQGAP1
chr15
90388242
90502239
+
SND1
chr7
127652194
128092609
+
HLA-B
chr6
31269491
31357188
-
APEH
chr3
49674014
49683971
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-188-5p
chrX
50003517
50003537
+
hsa-miR-34c-5p
chr11
111513451
111513473
+
hsa-miR-324-5p
chr17
7223343
7223364
-
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-129-2-3p
chr11
43581450
43581471
+
hsa-miR-330-5p
chr19
45639049
45639070
-
hsa-miR-628-5p
chr15
55372991
55373012
-
hsa-miR-541-3p
chr14
101064548
101064569
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
MIR663AHG
chr20
26167817
26251546
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.