Entry Detail


General Information

Database ID:exR0511072
RNA Name:AHCTF1
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):246839098End Site(bp):246931967
External Links:ENSG00000153207



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ADGRL2
chr1
81306160
81992436
+
BBX
chr3
107522936
107811339
+
CTNND1
chr11
57753243
57819546
+
DESI2
chr1
244653103
244709033
+
DIP2A
chr21
46458891
46570015
+
DYM
chr18
49041474
49461347
-
FAF1
chr1
50437028
50960267
-
FAM72D
chr1
145095974
145112696
+
FKBP8
chr19
18531751
18544077
-
GANAB
chr11
62624826
62646726
-
GATA4
chr8
11676959
11760002
+
KLHL42
chr12
27780048
27803040
+
OAZ1
chr19
2269509
2273490
+
OS9
chr12
57693955
57721557
+
PML
chr15
73994673
74047827
+
PPP2R2A
chr8
26291508
26372680
+
PTMA
chr2
231706895
231713541
+
RPL18
chr19
48615328
48619184
-
RPS8
chr1
44775251
44778779
+
RRM2B
chr8
102204502
102238961
-
RTN3
chr11
63681446
63759891
+
SDHC
chr1
161314257
161375340
+
SRSF9
chr12
120461672
120469748
-
STK35
chr20
2101827
2177038
+
UBE4B
chr1
10032832
10181239
+
ZSWIM8
chr10
73785582
73801797
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
FTX
chrX
73940435
74293574
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.