Entry Detail


General Information

Database ID:exR0511074
RNA Name:AHCYL1
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):109984765End Site(bp):110023742
External Links:ENSG00000168710



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HDGF
chr1
156742109
156766925
-
PAK2
chr3
196739857
196832647
+
DCUN1D4
chr4
51843000
51916837
+
NUFIP2
chr17
29255839
29294148
-
ATP5MF
chr7
99448475
99466331
-
NACA
chr12
56712427
56731628
-
RPLP0
chr12
120196699
120201235
-
NECAB3
chr20
33657087
33674463
-
TPT1
chr13
45333471
45341370
-
INTS10
chr8
19817391
19852083
+
RPS12
chr6
132814569
132817564
+
RRM2B
chr8
102204502
102238961
-
ERP44
chr9
99979185
100099000
-
UBXN6
chr19
4444999
4457794
-
TUBA1B
chr12
49127782
49131397
-
ATP5PO
chr21
33903453
33915814
-
HSP90AB1
chr6
44246166
44253888
+
IMMT
chr2
86143932
86195770
-
TKT
chr3
53224712
53256052
-
MT-ND4
chrMT
10760
12137
+
HLA-DRB1
chr6
32578769
32589848
-
AL136454.1
chr1
192716132
192716653
+
SYNCRIP
chr6
85607785
85643792
-
SLC1A5
chr19
46774883
46788594
-
NRM
chr6
30688047
30691420
-
OPA3
chr19
45527427
45602212
-
PABPN1
chr14
23321289
23326185
+
DDIT4
chr10
72273924
72276036
+
RPS10-NUDT3
chr6
34284887
34426071
-
IDH1
chr2
208236227
208266074
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-574-5p
chr4
38868056
38868078
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC073529.1
chrX
10847578
11111220
-
AC092490.1
chr12
8788253
8795789
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AC079354.2
chr2
202178660
202179391
-
LINC02190
chr16
31542748
31553604
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.