Entry Detail


General Information

Database ID:exR0511076
RNA Name:AHDC1
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):27534035End Site(bp):27604431
External Links:ENSG00000126705



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MTRNR2L10
chrX
55181392
55182442
-
EFNB2
chr13
106489745
106535662
-
DCUN1D4
chr4
51843000
51916837
+
PI4KA
chr22
20707691
20859417
-
PABPC1
chr8
100685816
100722809
-
PTBP1
chr19
797075
812327
+
TMEM107
chr17
8172457
8176399
-
ALDOA
chr16
30064164
30070457
+
ATRAID
chr2
27212027
27217178
+
LOXL3
chr2
74532258
74555690
-
FAM32A
chr19
16185380
16192046
+
EDARADD
chr1
236348257
236502915
+
EDC4
chr16
67873052
67884499
+
NUP188
chr9
128947699
129007096
+
ARHGAP33
chr19
35774532
35788822
+
SLC25A33
chr1
9539465
9585173
+
EP400
chr12
131949942
132080460
+
AIF1L
chr9
131096476
131123152
+
PRR14L
chr22
31676256
31750140
-
LPGAT1
chr1
211743457
211830763
-
RPS5
chr19
58386400
58394806
+
HCLS1
chr3
121631399
121660927
-
TOE1
chr1
45340052
45343973
+
CDK10
chr16
89680737
89696354
+
ATP1A1
chr1
116372668
116410261
+
NCBP1
chr9
97633668
97673748
+
CRTC1
chr19
18683678
18782333
+
WDR45B
chr17
82614562
82648553
-
GMEB2
chr20
63587602
63627101
-
RMI2
chr16
11249619
11381662
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-138-5p
chr16
56858527
56858549
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC138932.3
chr16
14909887
14911345
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.