Entry Detail


General Information

Database ID:exR0511078
RNA Name:AHNAK
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):62433542End Site(bp):62556235
External Links:ENSG00000124942



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SRRM2
chr16
2752626
2772538
+
C15orf39
chr15
75195643
75212169
+
DGKI
chr7
137381037
137847092
-
LRRC8A
chr9
128882112
128918039
+
PPP1R8
chr1
27830782
27851676
+
COMT
chr22
19941733
19969975
+
SLC16A1
chr1
112911847
112957013
-
RBM33
chr7
155644451
155781485
+
PSMD8
chr19
38374536
38383824
+
PSMB1
chr6
170535120
170553307
-
DNMT3A
chr2
25227855
25342590
-
PABPC3
chr13
25095868
25099254
+
TOR1AIP2
chr1
179839967
179877803
-
APP
chr21
25880550
26171128
-
MPZL1
chr1
167721192
167791919
+
DCAF8
chr1
160215715
160262549
-
FBXO31
chr16
87326987
87392142
-
SORL1
chr11
121452314
121633763
+
RABEP1
chr17
5282265
5386340
+
ARL2BP
chr16
57245259
57253635
+
HUWE1
chrX
53532096
53686728
-
RACK1
chr5
181236897
181248096
-
KDM6A
chrX
44873177
45112602
+
CCNG2
chr4
77157207
77433388
+
TMEM132A
chr11
60924463
60937159
+
PPP6R1
chr19
55229779
55259017
-
R3HCC1
chr8
23270120
23296279
+
TTC38
chr22
46267961
46294008
+
MFN2
chr1
11980181
12013514
+
MORF4L2
chrX
103675496
103688158
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC010327.5
chr19
55216660
55221616
+
AD000090.1
chr19
35557956
35581954
+
AL139385.1
chr13
110613082
110616353
-
LINC00174
chr7
66376044
66493566
-
RMRP
chr9
35657751
35658018
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.