Entry Detail


General Information

Database ID:exR0511080
RNA Name:AHR
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):16916359End Site(bp):17346152
External Links:ENSG00000106546



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AKR1A1
chr1
45550543
45570049
+
AP3B1
chr5
78000525
78294755
-
CAPRIN1
chr11
34051731
34102610
+
CCDC91
chr12
28133249
28581511
+
CNN3
chr1
94896949
94927223
-
COMMD1
chr2
61888724
62147247
+
DCAF6
chr1
167935783
168075843
+
FLT4
chr5
180601506
180649624
-
GAPDH
chr12
6534512
6538374
+
HMGB2
chr4
173331376
173334432
-
LGALS9
chr17
27629798
27649560
+
MED28
chr4
17614641
17634105
+
NAGK
chr2
71064344
71079808
+
NOP53
chr19
47745546
47757058
+
PTBP1
chr19
797075
812327
+
RFTN1
chr3
16313574
16514026
-
RPS23
chr5
82273320
82278396
-
RPS5
chr19
58386400
58394806
+
SLC2A3
chr12
7919230
7936187
-
SRF
chr6
43171269
43181506
+
SRP9
chr1
225777813
225790468
+
USP53
chr4
119212587
119295517
+
YIPF6
chrX
68498562
68537282
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC019117.3
chr7
17374867
17467256
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.