Entry Detail


General Information

Database ID:exR0511085
RNA Name:AIF1
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):31615217End Site(bp):31617021
External Links:ENSG00000204472



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AACS
chr12
125065434
125143333
+
AC008403.1
chr19
48465837
48472431
+
ANP32B
chr9
97983341
98015943
+
CCT7
chr2
73233420
73253021
+
COX7A2L
chr2
42333546
42425088
-
CYTH2
chr19
48469208
48482314
+
DAXX
chr6
33318558
33323016
-
GCK
chr7
44143213
44198170
-
IAH1
chr2
9473658
9496543
+
LEF1
chr4
108047545
108168956
-
NDUFA4
chr7
10931943
10940153
-
NDUFB9
chr8
124539101
124580648
+
RACK1
chr5
181236897
181248096
-
RBPJ
chr4
26163455
26435131
+
RPL27A
chr11
8682788
8714759
+
RPL37A
chr2
216498825
216579180
+
RPLP2
chr11
809965
812880
+
SIPA1L3
chr19
37907208
38208369
+
SRP9
chr1
225777813
225790468
+
TCF15
chr20
603797
610398
-
TUBA1A
chr12
49184795
49189080
-
UQCC3
chr11
62670273
62673686
+
ZNF322
chr6
26634383
26659752
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.