Entry Detail


General Information

Database ID:exR0511086
RNA Name:AIF1L
RNA Type:mRNA
Chromosome:chr9
Starnd:+
Coordinate:
Start Site(bp):131096476End Site(bp):131123152
External Links:ENSG00000126878



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
APEX1
chr14
20455191
20457772
+
HSPD1
chr2
197486584
197516737
-
SNRPG
chr2
70281362
70293740
-
SHC1
chr1
154962298
154974395
-
AC008763.2
chr19
7629796
7643048
+
PIM2
chrX
48913182
48919024
-
HSP90AB1
chr6
44246166
44253888
+
MT-ND2
chrMT
4470
5511
+
ALDH16A1
chr19
49453225
49471050
+
HK1
chr10
69269984
69401884
+
RPL11
chr1
23691742
23696835
+
PDS5B
chr13
32586452
32778019
+
MIF
chr22
23894383
23895227
+
XRCC5
chr2
216107464
216206303
+
C17orf113
chr17
42038232
42050601
-
TUBA1C
chr12
49188736
49274603
+
LRRC75A
chr17
16441577
16492193
-
OTUD1
chr10
23439458
23442390
+
INTS3
chr1
153728050
153774808
+
ZNF449
chrX
135344796
135363413
+
FTH1
chr11
61959718
61967634
-
SRPRB
chr3
133784023
133825772
+
MARCKSL1
chr1
32333839
32336233
-
MCM3AP
chr21
46235133
46286297
-
PCDHGB5
chr5
141397987
141512979
+
ERH
chr14
69380128
69398299
-
PPCDC
chr15
75023586
75117462
+
SMARCD1
chr12
50085200
50100707
+
RPL18
chr19
48615328
48619184
-
RBM14
chr11
66616582
66627347
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-641
chr19
40282603
40282626
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008267.5
chr7
66493607
66495758
+
AC069503.1
chr12
122007434
122020063
-
AL021707.3
chr22
38734730
38738990
+
MIR663AHG
chr20
26167817
26251546
-
NEAT1
chr11
65422774
65445540
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.