Entry Detail


General Information

Database ID:exR0511088
RNA Name:AIFM2
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):70098223End Site(bp):70132934
External Links:ENSG00000042286



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AACS
chr12
125065434
125143333
+
AC105052.1
chr7
102582523
102642869
-
BTF3
chr5
73498408
73505635
+
DCP2
chr5
112976702
113022195
+
DNM2
chr19
10718079
10833488
+
FOXM1
chr12
2857681
2877155
-
FTL
chr19
48965309
48966879
+
GPX4
chr19
1103926
1106791
+
HMGN1
chr21
39342315
39349647
-
MT-CO3
chrMT
9207
9990
+
MUTYH
chr1
45329163
45340893
-
PAFAH1B1
chr17
2593210
2685615
+
PGK1
chrX
77910739
78129295
+
PLEKHM2
chr1
15684320
15734769
+
RASA4
chr7
102573807
102616757
-
RPL13
chr16
89560657
89566828
+
RPLP2
chr11
809965
812880
+
TPT1
chr13
45333471
45341370
-
TYSND1
chr10
70137981
70146700
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.