Entry Detail


General Information

Database ID:exR0511090
RNA Name:AIG1
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):143060496End Site(bp):143341058
External Links:ENSG00000146416



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NARS2
chr11
78435968
78574874
-
MYO1G
chr7
44962662
44979088
-
ARHGAP30
chr1
161046946
161069970
-
AREL1
chr14
74653437
74713108
-
UBE3A
chr15
25333728
25439051
-
ATP2B4
chr1
203626561
203744081
+
DTWD1
chr15
49621037
49656232
+
RND2
chr17
43025231
43032041
+
CYP26A1
chr10
93073475
93077885
+
RGS12
chr4
3293028
3439913
+
MT-CO2
chrMT
7586
8269
+
ATRX
chrX
77504878
77786233
-
AC131160.1
chr3
183815568
183884889
-
HSP90AB1
chr6
44246166
44253888
+
DPP8
chr15
65442463
65517704
-
PPP1R8
chr1
27830782
27851676
+
EIF4B
chr12
53006158
53042209
+
FKBP1A
chr20
1368978
1393172
-
TUBB
chr6
30720352
30725426
+
HS1BP3
chr2
20560448
20651130
-
ARRB2
chr17
4710596
4721499
+
RNH1
chr11
494512
507300
-
BOD1
chr5
173607145
173616659
-
RPLP1
chr15
69452814
69456205
+
GNAS
chr20
58839718
58911192
+
WDR12
chr2
202874782
203014798
-
SLC43A3
chr11
57406954
57427580
-
ST3GAL2
chr16
70375977
70439237
-
TEX10
chr9
100302077
100352942
-
IGFBP4
chr17
40443450
40457725
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC137630.2
chr3
48979918
48983985
-
HOTAIRM1
chr7
27095647
27100265
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.