Entry Detail


General Information

Database ID:exR0511092
RNA Name:AIMP2
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):6009255End Site(bp):6023834
External Links:ENSG00000106305



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC026954.2
chr17
7312661
7319174
-
RPL36
chr19
5674947
5691875
+
TFG
chr3
100709331
100748964
+
CCDC163
chr1
45493866
45500079
-
RPL19
chr17
39200283
39204732
+
PAICS
chr4
56435741
56464579
+
CDK16
chrX
47217860
47229997
+
AC139530.2
chr17
81703371
81720539
+
IMP3
chr15
75639085
75648706
-
EPN1
chr19
55675226
55709858
+
NDUFV1
chr11
67605653
67612554
+
BFAR
chr16
14632931
14669236
+
PRR13
chr12
53441678
53446645
+
NMT1
chr17
45051610
45109016
+
EEF2
chr19
3976056
3985463
-
FTSJ3
chr17
63819433
63830012
-
CYP51A1
chr7
92112153
92134803
-
BZW1
chr2
200810594
200827338
+
MIF
chr22
23894383
23895227
+
MCL1
chr1
150574551
150579738
-
DYNLL1
chr12
120469850
120498493
+
SNX30
chr9
112750760
112881671
+
SMO
chr7
129188633
129213545
+
GLUL
chr1
182381704
182392206
-
KDM4B
chr19
4969113
5153598
+
FBRS
chr16
30658431
30670810
+
RNASEK-C17orf49
chr17
7012635
7017520
+
NFE2L1
chr17
48048329
48061545
+
CTSB
chr8
11842524
11869448
-
CTNNBL1
chr20
37693955
37872129
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
ATP2B1-AS1
chr12
89708959
89712590
+
STAG3L5P-PVRIG2P-PILRB
chr7
100336104
100367831
+
TPT1-AS1
chr13
45341345
45417975
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.