Entry Detail


General Information

Database ID:exR0511093
RNA Name:AIP
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):67483026End Site(bp):67491103
External Links:ENSG00000110711



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EWSR1
chr22
29268009
29300525
+
EMC10
chr19
50476400
50490870
+
LDHA
chr11
18394560
18408425
+
ANKRD13D
chr11
67289300
67302485
+
EIF3F
chr11
7970251
8001862
+
MKNK2
chr19
2037465
2051244
-
MAOA
chrX
43654907
43746824
+
DNA2
chr10
68414064
68472121
-
PKM
chr15
72199029
72231822
-
AP2M1
chr3
184174689
184184091
+
BCL2L13
chr22
17628855
17730855
+
RPS3
chr11
75399515
75422280
+
BHLHE22
chr8
64580365
64583627
+
TMX2
chr11
57712593
57740973
+
NOL6
chr9
33461353
33473930
-
APH1A
chr1
150265399
150269580
-
DMAC1
chr9
7796500
7888380
-
GLO1
chr6
38675925
38703145
-
OXLD1
chr17
81665036
81666635
-
HILPDA
chr7
128455849
128458418
+
UIMC1
chr5
176905005
177022633
-
AP002990.1
chr11
62559603
62591531
-
NOP53
chr19
47745546
47757058
+
GTF2A2
chr15
59638062
59657541
-
NIPSNAP1
chr22
29554808
29581327
-
VSTM2A
chr7
54542325
54571080
+
SLC25A6
chrX
1386152
1392113
-
LY6E
chr8
143017982
143023832
+
MADD
chr11
47269161
47330031
+
ALCAM
chr3
105366909
105576900
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005785.1
chr19
15379076
15381194
+
AD000090.1
chr19
35557956
35581954
+
FBXL19-AS1
chr16
30919319
30923269
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.