Entry Detail


General Information

Database ID:exR0511097
RNA Name:AK1
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):127866486End Site(bp):127877675
External Links:ENSG00000106992



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD17C
chr15
80679684
80755621
+
BCL11B
chr14
99169287
99272197
-
C9orf16
chr9
128160265
128163924
+
CBR3
chr21
36135079
36146562
+
CBX5
chr12
54230942
54280133
-
CLASP1
chr2
121337776
121649587
-
DBNDD1
chr16
90004871
90020128
-
ECI1
chr16
2239402
2252300
-
EIF4A1
chr17
7572706
7579006
+
HNRNPA1P48
chr16
51553436
51647132
+
HNRNPA3
chr2
177212563
177223958
+
IGFBP2
chr2
216632828
216664436
+
KANK1
chr9
470291
746106
+
LCMT1
chr16
25111731
25178231
+
MANEAL
chr1
37793802
37801137
+
MBNL1
chr3
152243828
152465780
+
NIP7
chr16
69337996
69343106
+
PRCP
chr11
82822936
82970584
-
RPS12
chr6
132814569
132817564
+
RPS19
chr19
41860255
41872925
+
SAP30L
chr5
154445997
154461053
+
SENP3-EIF4A1
chr17
7563287
7578715
+
SLC44A2
chr19
10602457
10644557
+
SYNRG
chr17
37514807
37609472
-
TBCEL
chr11
121024072
121090775
+
YTHDF2
chr1
28736621
28769775
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AL157935.2
chr9
127934503
127940952
+
SNHG5
chr6
85650491
85678932
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.