Entry Detail


General Information

Database ID:exR0511098
RNA Name:AK2
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):33007940End Site(bp):33080996
External Links:ENSG00000004455



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
IFI30
chr19
18173162
18178117
+
C19orf53
chr19
13774456
13778773
+
RBM10
chrX
47145221
47186813
+
RPL5
chr1
92832013
92841924
+
SAP30BP
chr17
75667251
75708062
+
PPP2CA
chr5
134194332
134226073
-
RPLP1
chr15
69452814
69456205
+
REXO1
chr19
1815248
1848483
-
ARL2BP
chr16
57245259
57253635
+
GTF3C5
chr9
133030675
133058503
+
GRID1
chr10
85599552
86366795
-
OGFOD3
chr17
82389210
82418637
-
MRPL4
chr19
10251901
10260055
+
EIF4E
chr4
98871684
98930637
-
DDIT4
chr10
72273924
72276036
+
MYBBP1A
chr17
4538897
4555631
-
MZT1
chr13
72708367
72727629
-
AC011448.1
chr19
19516227
19536076
+
MTRNR2L1
chr17
22523111
22524663
+
CDC42SE1
chr1
151050971
151070325
-
HAUS1
chr18
46104378
46128333
+
POMP
chr13
28659104
28678959
+
AP2A1
chr19
49766968
49807113
+
HLA-B
chr6
31269491
31357188
-
OCIAD1
chr4
48805212
48861817
+
MAL2
chr8
119165034
119245673
+
RPS5
chr19
58386400
58394806
+
HLA-DQB1
chr6
32659467
32668383
-
STRAP
chr12
15882387
15903478
+
SLC25A37
chr8
23528956
23575463
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-204-5p
chr9
70810031
70810052
-
hsa-miR-211-5p
chr15
31065095
31065116
-
hsa-miR-141-3p
chr12
6964155
6964176
+
hsa-miR-299-3p
chr14
101023832
101023853
+
hsa-miR-1224-5p
chr3
184241405
184241423
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009133.5
chr16
29808679
29812227
+
AL121985.1
chr1
160670778
160699761
+
GUSBP11
chr22
23638487
23717356
-
LINC02381
chr12
54126082
54147485
+
LINC02539
chr6
137730170
137792835
-
MALAT1
chr11
65497688
65506516
+
SNHG17
chr20
38419638
38435409
-
SNHG5
chr6
85650491
85678932
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.