Entry Detail


General Information

Database ID:exR0511099
RNA Name:AK3
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):4709556End Site(bp):4742043
External Links:ENSG00000147853



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CD74
chr5
150400041
150412929
-
BAZ2A
chr12
56595596
56636816
-
ERCC3
chr2
127257290
127294166
-
MT-ATP6
chrMT
8527
9207
+
RPLP0
chr12
120196699
120201235
-
DYNC1H1
chr14
101964573
102056443
+
TPRN
chr9
137191617
137204193
-
ATP1A1
chr1
116372668
116410261
+
FNDC5
chr1
32862268
32872482
-
BX255925.3
chr9
137217452
137219361
+
CD9
chr12
6199715
6238271
+
THOC6
chr16
3024027
3027755
+
RAB7A
chr3
128726183
128814798
+
RPS3
chr11
75399515
75422280
+
APTX
chr9
32886601
33025130
-
EIF5
chr14
103333544
103345025
+
GAPDH
chr12
6534512
6538374
+
ZNF280D
chr15
56630181
56734086
-
BRK1
chr3
10115675
10127190
+
FZD3
chr8
28494205
28574267
+
FBXO38
chr5
148383935
148442836
+
MTFR1L
chr1
25818640
25832942
+
RPS17
chr15
82536750
82540459
-
RPL17
chr18
49488453
49492523
-
ZNF8
chr19
58278955
58302791
+
CHD4
chr12
6570082
6614524
-
WDR11
chr10
120851305
120909524
+
SELENOO
chr22
50200979
50217616
+
RPL32
chr3
12834485
12841582
-
ACTG1
chr17
81509971
81523847
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
HOTAIRM1
chr7
27095647
27100265
+
NBR2
chr17
43125551
43153671
+
OIP5-AS1
chr15
41283990
41309737
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.