Entry Detail


General Information

Database ID:exR0511102
RNA Name:AKAP10
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):19904302End Site(bp):19978343
External Links:ENSG00000108599



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TCERG1
chr5
146447311
146511961
+
EFNB2
chr13
106489745
106535662
-
MCFD2
chr2
46901870
46941855
-
ZNF850
chr19
36714383
36772825
-
ATP5MC2
chr12
53632726
53677408
-
PTPRF
chr1
43525187
43623666
+
NSMF
chr9
137447573
137459334
-
GUF1
chr4
44678420
44700928
+
AMPD2
chr1
109616104
109632053
+
MTG2
chr20
62183029
62203568
+
AASDHPPT
chr11
106075501
106098699
+
PROM1
chr4
15963076
16084378
-
RPL27
chr17
42998273
43002959
+
MICALL1
chr22
37905657
37942822
+
ZNF24
chr18
35332227
35345482
-
CSNK1E
chr22
38290691
38318084
-
ICMT
chr1
6221193
6235972
-
ZFAND3
chr6
37819727
38154624
+
SBNO2
chr19
1107637
1174268
-
OGT
chrX
71533104
71575892
+
FOXK2
chr17
82519713
82644662
+
CANX
chr5
179678628
179731641
+
VMP1
chr17
59707192
59842255
+
CREBL2
chr12
12611827
12645108
+
GIGYF2
chr2
232697299
232860575
+
TNFSF9
chr19
6531026
6535924
+
SOBP
chr6
107490106
107661306
+
AP2A2
chr11
924894
1012245
+
SLC35F2
chr11
107790991
107928293
-
AP002990.1
chr11
62559603
62591531
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-130a-3p
chr11
57641252
57641273
+
hsa-miR-130b-3p
chr22
21653354
21653375
+
hsa-miR-454-3p
chr17
59137787
59137809
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079949.1
chr12
127142029
127146532
-
AL645608.1
chr1
1011997
1013193
-
TMEM147-AS1
chr19
35540738
35546029
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.