Entry Detail


General Information

Database ID:exR0511103
RNA Name:AKAP11
RNA Type:mRNA
Chromosome:chr13
Starnd:+
Coordinate:
Start Site(bp):42272152End Site(bp):42323261
External Links:ENSG00000023516



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005670.2
chr17
46923133
47049932
+
MAPK1
chr22
21754500
21867680
-
ZNF100
chr19
21722771
21767579
-
CANX
chr5
179678628
179731641
+
TPI1
chr12
6867119
6870948
+
AIFM1
chrX
130129362
130165887
-
RAB3GAP2
chr1
220148293
220272453
-
TOP3A
chr17
18271428
18315007
-
NOC2L
chr1
944203
959309
-
DYRK1A
chr21
37365573
37526358
+
PSMB1
chr6
170535120
170553307
-
CSNK1A1
chr5
149492982
149551471
-
ZNF711
chrX
85244032
85273362
+
RPL15
chr3
23916545
23924374
+
C16orf91
chr16
1419752
1420756
-
ATP13A2
chr1
16985958
17011928
-
NPTX2
chr7
98617285
98629869
+
EDARADD
chr1
236348257
236502915
+
MAZ
chr16
29806106
29811164
+
SEC31A
chr4
82818509
82901166
-
HOMEZ
chr14
23272422
23299447
-
PIK3CB
chr3
138652698
138834928
-
HLA-DRB1
chr6
32578769
32589848
-
CCT8
chr21
29055805
29073797
-
FSCN1
chr7
5592816
5606655
+
RPL22
chr1
6185020
6209389
-
CXXC5
chr5
139647299
139683882
+
LDHA
chr11
18394560
18408425
+
CMPK1
chr1
47333797
47378839
+
KCMF1
chr2
84971093
85059472
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-130a-3p
chr11
57641252
57641273
+
hsa-miR-362-3p
chrX
50009005
50009026
+
hsa-miR-541-3p
chr14
101064548
101064569
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
MEG3
chr14
100779410
100861031
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.