Entry Detail


General Information

Database ID:exR0511104
RNA Name:AKAP12
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):151239967End Site(bp):151358559
External Links:ENSG00000131016



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MAVS
chr20
3846799
3876123
+
CALM1
chr14
90396502
90408268
+
AP1B1
chr22
29327680
29423179
-
SLC25A3
chr12
98593591
98606379
+
MEPCE
chr7
100428790
100434118
+
PLCXD1
chrX
276322
303356
+
CEP68
chr2
65056366
65087004
+
ARNT
chr1
150809713
150876708
-
SLC3A2
chr11
62856102
62888875
+
PAQR3
chr4
78887127
78939438
-
RAB3GAP1
chr2
135052265
135176394
+
ACTG1
chr17
81509971
81523847
-
TMBIM6
chr12
49707725
49764934
+
ZNF646
chr16
31074422
31084196
+
PSME4
chr2
53864069
53970993
-
TAF10
chr11
6606294
6612539
-
LAMP1
chr13
113297239
113323672
+
HNRNPF
chr10
43385617
43409166
-
ADGRG6
chr6
142301854
142446266
+
SNX3
chr6
108211222
108261246
-
GPHN
chr14
66507407
67181803
+
PARN
chr16
14435700
14632728
-
UNC45A
chr15
90930180
90954093
+
HERC2
chr15
28111040
28322172
-
B4GALT4
chr3
119211732
119240946
-
DSTN
chr20
17570075
17609919
+
ADGRL1
chr19
14147743
14206187
-
MTHFD2
chr2
74198610
74217565
+
SC5D
chr11
121292681
121313410
+
STT3B
chr3
31532638
31637616
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC091564.7
chr11
6610883
6616594
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.