Entry Detail


General Information

Database ID:exR0511108
RNA Name:AKAP5
RNA Type:mRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):64465499End Site(bp):64474503
External Links:ENSG00000179841



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010463.1
chr19
17267418
17282966
+
AC023055.1
chr12
55757275
55827546
-
BABAM1
chr19
17267376
17281249
+
CNPY3
chr6
42929192
42939294
+
EIF3I
chr1
32221928
32231604
+
GNB1
chr1
1785285
1891117
-
PPP2R1B
chr11
111726908
111766389
-
PSMB5
chr14
23016543
23035230
-
RPS16
chr19
39433137
39435949
-
RPS3
chr11
75399515
75422280
+
SARNP
chr12
55752463
55817724
-
ZNF141
chr4
337814
384868
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.