Entry Detail


General Information

Database ID:exR0511113
RNA Name:AKIRIN1
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):38991276End Site(bp):39006059
External Links:ENSG00000174574



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CHIC2
chr4
54009789
54064605
-
NOP10
chr15
34341713
34343177
-
DDX54
chr12
113157174
113185479
-
RBM39
chr20
35701347
35742312
-
MCFD2
chr2
46901870
46941855
-
KIAA0319L
chr1
35433492
35557950
-
SH2B3
chr12
111405923
111451623
+
IST1
chr16
71845996
71931199
+
KMT5C
chr19
55339853
55348121
+
CCNB1IP1
chr14
20311368
20333312
-
PJA2
chr5
109334713
109409974
-
DNAJB9
chr7
108569867
108574850
+
RAB3B
chr1
51907956
51990700
-
ANKRD17
chr4
73073376
73258798
-
EIF3B
chr7
2354086
2380745
+
PPP1CC
chr12
110719680
110742939
-
SLC38A1
chr12
46183063
46270017
-
CTSD
chr11
1752755
1764573
-
EIF4H
chr7
74174245
74197101
+
C12orf65
chr12
123233436
123257960
+
TFRC
chr3
196027183
196082096
-
TXNDC5
chr6
7881517
7910788
-
G3BP1
chr5
151771045
151812785
+
EP400
chr12
131949942
132080460
+
ZFC3H1
chr12
71609472
71667725
-
TKT
chr3
53224712
53256052
-
CKS2
chr9
89311195
89316703
+
TXN
chr9
110243810
110256507
-
EPAS1
chr2
46293667
46386697
+
ASB1
chr2
238426742
238452250
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-367-3p
chr4
112647877
112647898
-
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC138761.1
chr17
22266395
22288301
+
AP001496.2
chr18
5232876
5238526
-
ARSD-AS1
chrX
2904904
2906081
+
LINC01783
chr1
16533886
16536172
-
MAPKAPK5-AS1
chr12
111839764
111842902
-
SCARNA9
chr11
93721513
93721865
+
SNHG5
chr6
85650491
85678932
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.