Entry Detail


General Information

Database ID:exR0512204
RNA Name:C19orf53
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):13774456End Site(bp):13778773
External Links:ENSG00000104979



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC124312.1
chr15
24955034
25000276
+
ACOT8
chr20
45841721
45857405
-
ACTR1A
chr10
102461881
102502712
-
ACTR2
chr2
65227753
65271253
+
AHCY
chr20
34280268
34311802
-
AK2
chr1
33007940
33080996
-
AL121753.1
chr20
35267885
35280043
-
AL603832.3
chr1
112702614
112711433
-
AL928654.3
chr14
105487199
105492267
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-let-7a-5p
chr9
94175962
94175983
+
hsa-let-7b-5p
chr22
46113691
46113712
+
hsa-let-7e-5p
chr19
51692793
51692814
+
hsa-miR-196a-5p
chr17
48632532
48632553
-
hsa-miR-196b-5p
chr7
27169528
27169549
-
hsa-miR-541-3p
chr14
101064548
101064569
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.