Entry Detail


General Information

Database ID:exR0512361
RNA Name:C7orf50
RNA Type:mRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):996986End Site(bp):1138260
External Links:ENSG00000146540



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC003006.1
chr19
57682045
57753575
+
AC004832.3
chr22
30409255
30428990
+
AC010422.3
chr19
12643831
12648397
-
AC040162.1
chr16
67929614
67936017
-
ACTB
chr7
5527148
5563784
-
ADAMTS1
chr21
26835755
26845409
-
ADM2
chr22
50481543
50486440
+
AKNA
chr9
114334156
114394405
-
AKR1A1
chr1
45550543
45570049
+
AKT2
chr19
40230317
40285536
-
AL162417.1
chr9
133098121
133163914
-
AL928654.3
chr14
105487199
105492267
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010442.1
chr5
466124
473098
-
AL118506.1
chr20
63861212
63864293
-
AL136090.1
chr20
19212852
19213477
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.