Entry Detail


General Information

Database ID:exR0512739
RNA Name:CCNG1
RNA Type:mRNA
Chromosome:chr5
Starnd:+
Coordinate:
Start Site(bp):163437569End Site(bp):163446151
External Links:ENSG00000113328



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
ABRACL
chr6
139028745
139043302
+
AC008581.2
chr5
77030902
77152155
+
AC023055.1
chr12
55757275
55827546
-
ACSL4
chrX
109624244
109733403
-
ACTR10
chr14
58200080
58235636
+
ACTR2
chr2
65227753
65271253
+
ADAMTS1
chr21
26835755
26845409
-
ADK
chr10
74151202
74709963
+
AGAP3
chr7
151085831
151144436
+
AGFG1
chr2
227472152
227561214
+
AGGF1
chr5
77029251
77065234
+
AIFM1
chrX
130129362
130165887
-
AL133352.1
chr10
100505628
100529881
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-34c-5p
chr11
111513451
111513473
+
hsa-miR-526b-5p
chr19
53694406
53694428
+
hsa-miR-449b-5p
chr5
55170706
55170727
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC106864.1
chr4
112693047
112706810
-
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.