Entry Detail


General Information

Database ID:exR0513320
RNA Name:CLTA
RNA Type:mRNA
Chromosome:chr9
Starnd:+
Coordinate:
Start Site(bp):36190856End Site(bp):36304781
External Links:ENSG00000122705



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AARSD1
chr17
42950526
42964498
-
ABHD17C
chr15
80679684
80755621
+
ABL1
chr9
130713016
130887675
+
ABRACL
chr6
139028745
139043302
+
ABT1
chr6
26596953
26600739
+
AC010422.3
chr19
12643831
12648397
-
AC010646.1
chr19
17235940
17255448
-
AC092143.1
chr16
89919165
89936092
+
ACTB
chr7
5527148
5563784
-
ADD3
chr10
109996368
110135565
+
AIF1L
chr9
131096476
131123152
+
AKT1S1
chr19
49869033
49878459
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC106864.1
chr4
112693047
112706810
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.