Entry Detail


General Information

Database ID:exR0513650
RNA Name:CS
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):56271699End Site(bp):56300391
External Links:ENSG00000062485



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
ABCB9
chr12
122920951
122981649
-
ABHD10
chr3
111979010
111993368
+
AC004922.1
chr7
99325879
99394653
+
AC073896.1
chr12
56285916
56316059
-
AC138811.2
chr16
18788063
18801519
-
ACTR2
chr2
65227753
65271253
+
AHCYL1
chr1
109984765
110023742
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-196a-5p
chr17
48632532
48632553
-
hsa-miR-196b-5p
chr7
27169528
27169549
-
hsa-miR-431-5p
chr14
100881026
100881046
+
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-198
chr3
120395703
120395724
-
hsa-miR-5001-5p
chr2
232550530
232550553
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007218.1
chr16
9666885
9676843
-
AC008267.5
chr7
66493607
66495758
+
AC040977.2
chr17
6985494
7019414
-
AC115284.1
chr3
51961212
51974031
-
AL031595.3
chr22
44139365
44153626
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.