Entry Detail


General Information

Database ID:exR0513678
RNA Name:CSNK1E
RNA Type:mRNA
Chromosome:chr22
Starnd:-
Coordinate:
Start Site(bp):38290691End Site(bp):38318084
External Links:ENSG00000213923



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
AC091167.2
chr15
90249556
90272208
+
AC138969.1
chr16
16317444
16350590
+
ACAP3
chr1
1292390
1309609
-
ACBD3
chr1
226144679
226186741
-
ACTG1
chr17
81509971
81523847
-
ADCY1
chr7
45574140
45723116
+
ADGRB2
chr1
31727117
31764893
-
AFF1
chr4
86935002
87141054
+
AGPAT2
chr9
136673143
136687457
-
AKAP10
chr17
19904302
19978343
-
AKR1B1
chr7
134442356
134459284
-
AL157392.5
chr10
13610047
13655929
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-let-7d-5p
chr9
94178841
94178862
+
hsa-miR-491-5p
chr9
20716120
20716141
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-873-5p
chr9
28888925
28888945
-
hsa-miR-1286
chr22
20249145
20249165
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC132872.1
chr17
82293716
82294910
+
AL049543.1
chr6
28587378
28591747
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.