Entry Detail


General Information

Database ID:exR0513732
RNA Name:CTNNA1
RNA Type:mRNA
Chromosome:chr5
Starnd:+
Coordinate:
Start Site(bp):138610967End Site(bp):138935034
External Links:ENSG00000044115



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAK1
chr2
69457997
69674349
-
AAMP
chr2
218264123
218270257
-
AC011455.2
chr19
38915404
38949855
-
AC099811.2
chr17
42119674
42154916
-
ACIN1
chr14
23058564
23095614
-
ACSL3
chr2
222860942
222944639
+
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ADA2
chr22
17178790
17258235
-
ADARB1
chr21
45073853
45226560
+
ADD3
chr10
109996368
110135565
+
ADH5
chr4
99070978
99088801
-
ADNP
chr20
50888916
50931437
-
ADNP2
chr18
80109262
80147523
+
ADSL
chr22
40346500
40390463
+
AGPAT1
chr6
32168212
32178096
-
AIG1
chr6
143060496
143341058
+
AKAP8
chr19
15353385
15379798
-
AL022238.4
chr22
40346529
40410054
+
AL603832.3
chr1
112702614
112711433
-
ALDH16A1
chr19
49453225
49471050
+
ALDH2
chr12
111766887
111817532
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-320a-3p
chr8
22244975
22244996
-
hsa-miR-7705
chr8
100703002
100703024
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007405.3
chr2
170814686
170818037
-
AC018521.1
chr17
47945424
47981736
+
AC026304.1
chr3
143000907
143001467
-
AC092490.1
chr12
8788253
8795789
+
AC138035.1
chr5
181306502
181324685
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.