Entry Detail


General Information

Database ID:exR0513945
RNA Name:DCAF7
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):63550477End Site(bp):63594279
External Links:ENSG00000136485



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABRACL
chr6
139028745
139043302
+
AC092143.1
chr16
89919165
89936092
+
ACOT7
chr1
6264269
6394391
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADAM8
chr10
133262420
133276868
-
ADGRB2
chr1
31727117
31764893
-
AHCY
chr20
34280268
34311802
-
AHNAK
chr11
62433542
62556235
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-16-5p
chr3
160404754
160404775
+
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-107
chr10
89592756
89592778
-
hsa-miR-15b-5p
chr3
160404607
160404628
+
hsa-miR-195-5p
chr17
7017667
7017687
-
hsa-miR-346
chr10
86264747
86264769
-
hsa-miR-424-5p
chrX
134546680
134546701
-
hsa-miR-18b-5p
chrX
134170084
134170106
-
hsa-miR-514a-3p
chrX
147281957
147281977
-
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-1323
chr19
53671978
53671999
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010186.4
chr12
9642872
9657070
+
AC016876.2
chr17
7581964
7584086
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.