Entry Detail


General Information

Database ID:exR0513988
RNA Name:DDB1
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):61299451End Site(bp):61342596
External Links:ENSG00000167986



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
ABCB8
chr7
151028422
151047782
+
ABI2
chr2
203328239
203447728
+
ABRACL
chr6
139028745
139043302
+
AC005258.1
chr19
2269525
2341172
+
AC008982.1
chr19
38817471
38840178
-
AC011448.1
chr19
19516227
19536076
+
AC118549.1
chr1
77562416
77683419
-
ACBD6
chr1
180269653
180502954
-
ACIN1
chr14
23058564
23095614
-
ACSL1
chr4
184755595
184826818
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR3
chr2
113890063
113962596
+
ACTR8
chr3
53867066
53882152
-
ADAMTS1
chr21
26835755
26845409
-
ADAR
chr1
154582057
154628013
-
ADGRG6
chr6
142301854
142446266
+
AGO2
chr8
140520156
140635633
-
AGPAT4
chr6
161129967
161274061
-
AJUBA
chr14
22971177
22982551
-
AKR7A2
chr1
19303965
19312146
-
AKT1
chr14
104769349
104795751
-
AKT1S1
chr19
49869033
49878459
-
AL133352.1
chr10
100505628
100529881
-
AL136454.1
chr1
192716132
192716653
+
AL139011.2
chr1
160216800
160285130
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-155-5p
chr21
25573983
25574006
+
hsa-miR-367-3p
chr4
112647877
112647898
-
hsa-miR-155-3p
chr21
25574022
25574043
+
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012485.1
chr2
238231684
238255633
+
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AC124068.2
chr15
89335053
89336161
+
AC133644.3
chr2
87455476
87767359
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.