Entry Detail


General Information

Database ID:exR0513995
RNA Name:DDIT4
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):72273924End Site(bp):72276036
External Links:ENSG00000168209



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABI2
chr2
203328239
203447728
+
AC005258.1
chr19
2269525
2341172
+
AC006064.6
chr12
6556886
6607367
-
AC008982.1
chr19
38817471
38840178
-
AC010422.3
chr19
12643831
12648397
-
AC011462.1
chr19
41350853
41425001
+
AC011511.4
chr19
10315471
10320678
-
AC068547.1
chr2
151802651
151973949
-
AC092143.1
chr16
89919165
89936092
+
AC139530.2
chr17
81703371
81720539
+
ACLY
chr17
41866917
41930542
-
ACTA2
chr10
88935074
88991339
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR1B
chr2
97655939
97664044
-
ADAMTS12
chr5
33523535
33892019
-
ADAR
chr1
154582057
154628013
-
ADH5
chr4
99070978
99088801
-
ADM
chr11
10305073
10307397
+
ADRM1
chr20
62302093
62308862
+
AGFG1
chr2
227472152
227561214
+
AHCYL1
chr1
109984765
110023742
+
AIFM1
chrX
130129362
130165887
-
AK2
chr1
33007940
33080996
-
AKNA
chr9
114334156
114394405
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-221-3p
chrX
45746180
45746202
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004771.3
chr17
4967995
4968822
+
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AC025165.5
chr12
57803838
57804415
+
AC135048.1
chr16
30948386
30956511
+
AC234582.1
chr1
155195004
155205495
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.