Entry Detail


General Information

Database ID:exR0514008
RNA Name:DDX17
RNA Type:mRNA
Chromosome:chr22
Starnd:-
Coordinate:
Start Site(bp):38483438End Site(bp):38507660
External Links:ENSG00000100201



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
AAR2
chr20
36236459
36270918
+
AATF
chr17
36948954
37056871
+
ABHD8
chr19
17292131
17310236
-
AC005258.1
chr19
2269525
2341172
+
AC006064.6
chr12
6556886
6607367
-
AC007998.2
chr18
35443871
35497940
-
AC015813.2
chr17
57989038
58007246
-
AC107871.1
chr15
68184032
68229718
-
AC120057.2
chr17
7240427
7244635
-
ACIN1
chr14
23058564
23095614
-
ACTB
chr7
5527148
5563784
-
ACTN1
chr14
68874143
68979440
-
ACVR2A
chr2
147844517
147930826
+
ACVR2B
chr3
38453890
38493142
+
ADAM10
chr15
58588809
58749791
-
ADAM19
chr5
157395534
157575775
-
ADAR
chr1
154582057
154628013
-
ADD1
chr4
2843857
2930076
+
AEN
chr15
88621337
88632281
+
AHCY
chr20
34280268
34311802
-
AKT2
chr19
40230317
40285536
-
AL133352.1
chr10
100505628
100529881
-
AL136295.5
chr14
24147548
24166452
+
AL136454.1
chr1
192716132
192716653
+
AL358113.1
chr9
69035747
69255187
+
AL928654.3
chr14
105487199
105492267
+
ALDH16A1
chr19
49453225
49471050
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302d-3p
chr4
112648006
112648028
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC007998.3
chr18
35443869
35467088
-
AC016876.2
chr17
7581964
7584086
-
AC018809.2
chr3
9958717
9962539
+
AC067852.1
chr17
42536510
42562062
+
AC132217.1
chr11
2129121
2129964
-
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.