Entry Detail


General Information

Database ID:exR0514015
RNA Name:DDX24
RNA Type:mRNA
Chromosome:chr14
Starnd:-
Coordinate:
Start Site(bp):94048287End Site(bp):94081212
External Links:ENSG00000089737



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD14B
chr3
51968510
51983409
-
ABI2
chr2
203328239
203447728
+
AC093323.1
chr4
6663396
6676755
+
AC245033.1
chr15
82536788
82573194
-
ACADM
chr1
75724347
75787575
+
ACADSB
chr10
123008979
123058290
+
ACTR6
chr12
100199122
100241865
+
ADAMTS13
chr9
133414358
133459402
+
AGO1
chr1
35869808
35930532
+
AGPAT4
chr6
161129967
161274061
-
AKAP8
chr19
15353385
15379798
-
ALDH18A1
chr10
95605941
95656711
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002467.1
chr7
107739999
107744581
-
AC020910.5
chr19
34733298
34733837
-
AC115284.1
chr3
51961212
51974031
-
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.