Entry Detail


General Information

Database ID:exR0514126
RNA Name:DHCR24
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):54849627End Site(bp):54887195
External Links:ENSG00000116133



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABL1
chr9
130713016
130887675
+
AC004832.3
chr22
30409255
30428990
+
AC005258.1
chr19
2269525
2341172
+
AC008763.3
chr19
7678501
7682854
+
AC091167.2
chr15
90249556
90272208
+
AC120057.2
chr17
7240427
7244635
-
ACADSB
chr10
123008979
123058290
+
ACIN1
chr14
23058564
23095614
-
ACTA1
chr1
229431245
229434098
-
ADAR
chr1
154582057
154628013
-
ADGRA3
chr4
22345071
22516066
-
AK2
chr1
33007940
33080996
-
AKIRIN1
chr1
38991276
39006059
+
AKR1B1
chr7
134442356
134459284
-
AL136295.1
chr14
24189157
24213473
-
AL713999.1
chr1
155169409
155187272
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-7-5p
chr19
4770700
4770723
+
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-541-3p
chr14
101064548
101064569
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006064.5
chr12
6510275
6510522
+
AC016876.2
chr17
7581964
7584086
-
AC040162.3
chr16
67882461
67886367
+
AC244517.11
chr5
141136683
141245380
-
AD000090.1
chr19
35557956
35581954
+
AL096870.2
chr14
24209646
24215987
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.