Entry Detail


General Information

Database ID:exR0514261
RNA Name:DNAJB6
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):157335381End Site(bp):157417439
External Links:ENSG00000105993



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACER3
chr11
76860867
77026797
+
ACTR3
chr2
113890063
113962596
+
ADAMTS8
chr11
130404923
130428609
-
AFDN
chr6
167826922
167972023
+
AGPAT2
chr9
136673143
136687457
-
AGTPBP1
chr9
85546539
85742029
-
AHCY
chr20
34280268
34311802
-
AL031708.1
chr16
1632259
1686715
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-24-3p
chr9
95086064
95086085
+
hsa-miR-105-5p
chrX
152394458
152394480
-
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-877-5p
chr6
30584332
30584351
+
hsa-miR-1270
chr19
20399320
20399342
-
hsa-miR-4709-5p
chr14
74480175
74480196
-
hsa-miR-4709-3p
chr14
74480135
74480157
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC106864.1
chr4
112693047
112706810
-
AL035458.2
chr20
34234840
34281173
-
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.