Entry Detail


General Information

Database ID:exR0514377
RNA Name:DPYSL3
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):147390808End Site(bp):147510068
External Links:ENSG00000113657



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC10
chr6
43427366
43450427
+
ABRACL
chr6
139028745
139043302
+
AC006030.1
chr2
74211604
74363377
-
AC091167.2
chr15
90249556
90272208
+
AC092647.5
chr7
55887277
55955239
+
ACACA
chr17
37084992
37406836
-
ACTG1
chr17
81509971
81523847
-
ACTN1
chr14
68874143
68979440
-
ACTR3
chr2
113890063
113962596
+
ACVR1C
chr2
157526767
157628864
-
ADGRL1
chr19
14147743
14206187
-
AEBP2
chr12
19404045
19720801
+
AFDN
chr6
167826922
167972023
+
AGPAT1
chr6
32168212
32178096
-
AHCY
chr20
34280268
34311802
-
AKT1
chr14
104769349
104795751
-
ALDH18A1
chr10
95605941
95656711
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC021242.3
chr8
9555144
9556520
-
AC027031.2
chr8
106270144
106272902
+
AC079781.5
chr7
97851688
97972985
-
AC106864.1
chr4
112693047
112706810
-
AC108449.2
chr8
29055935
29056685
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.