Entry Detail


General Information

Database ID:exR0514405
RNA Name:DSP
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):7541617End Site(bp):7586714
External Links:ENSG00000096696



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC4
chr13
95019835
95301475
-
AC007192.1
chr19
18153158
18178117
+
AC026954.2
chr17
7312661
7319174
-
AC091167.2
chr15
90249556
90272208
+
AC118549.1
chr1
77562416
77683419
-
ACACA
chr17
37084992
37406836
-
ACTG1
chr17
81509971
81523847
-
ADNP
chr20
50888916
50931437
-
ADSL
chr22
40346500
40390463
+
AHDC1
chr1
27534035
27604431
-
AIF1L
chr9
131096476
131123152
+
AKIRIN2
chr6
87674860
87702233
-
AL022238.4
chr22
40346529
40410054
+
AL034430.1
chr20
10413520
10431922
-
ALDH1B1
chr9
38392702
38398661
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-138-5p
chr16
56858527
56858549
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL136531.1
chr20
1361622
1362585
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.