Entry Detail


General Information

Database ID:exR0514464
RNA Name:DYNC1H1
RNA Type:mRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):101964573End Site(bp):102056443
External Links:ENSG00000197102



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
AC090004.1
chr3
14135217
14148252
+
AC093525.1
chr16
2513965
2527955
+
AC093525.2
chr16
2496032
2520218
+
AC104109.3
chr5
134167170
134226071
-
AC138969.1
chr16
16317444
16350590
+
AC245033.1
chr15
82536788
82573194
-
ACAA2
chr18
49782164
49813953
-
ADAMTS15
chr11
130448974
130476641
+
ADCY3
chr2
24819169
24919839
-
ADD2
chr2
70607618
70768225
-
AGRN
chr1
1020120
1056118
+
AIF1L
chr9
131096476
131123152
+
AK3
chr9
4709556
4742043
-
AKAP1
chr17
57085092
57121346
+
AL139300.1
chr14
103562962
103685924
+
AL162417.1
chr9
133098121
133163914
-
ALDH18A1
chr10
95605941
95656711
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-21-5p
chr17
59841273
59841294
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005899.4
chr17
32328441
32329395
+
AC008124.1
chr12
45718046
45727775
-
AC110285.2
chr17
81388126
81390319
-
AC245014.3
chr1
145281116
145281462
+
AL022157.1
chrX
57121662
57127243
+
AL110115.2
chr20
31580890
31581214
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.