Entry Detail


General Information

Database ID:exR0514524
RNA Name:EDARADD
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):236348257End Site(bp):236502915
External Links:ENSG00000186197



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL136454.1
chr1
192716132
192716653
+
AL020996.2
chr1
25811470
25823744
+
AL035078.4
chr11
31812391
32104665
+
ACTR2
chr2
65227753
65271253
+
AKIRIN2
chr6
87674860
87702233
-
ACO1
chr9
32384603
32454769
+
AC245033.1
chr15
82536788
82573194
-
ADGRE5
chr19
14380501
14408725
+
AL138752.2
chr9
37588413
38068687
-
AKAP11
chr13
42272152
42323261
+
AC124312.1
chr15
24955034
25000276
+
ACAD10
chr12
111686056
111757107
+
ALDH2
chr12
111766887
111817532
+
AC068946.1
chr2
219075329
219170827
-
AKAP8
chr19
15353385
15379798
-
AKR1A1
chr1
45550543
45570049
+
ACTR8
chr3
53867066
53882152
-
AC004832.3
chr22
30409255
30428990
+
ACTG1
chr17
81509971
81523847
-
ACLY
chr17
41866917
41930542
-
AC020909.1
chr19
50415799
50428409
+
AK2
chr1
33007940
33080996
-
ACAD9
chr3
128879596
128916067
+
ABRAXAS2
chr10
124801819
124836667
+
AKR1B1
chr7
134442356
134459284
-
ADGRL2
chr1
81306160
81992436
+
ADPRH
chr3
119579268
119589945
+
AL355315.1
chr10
97584374
97673910
+
AC011462.1
chr19
41350853
41425001
+
AC005832.4
chr12
4604944
4662643
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-21-5p
chr17
59841273
59841294
+
hsa-miR-4426
chr1
192716333
192716349
+
hsa-miR-6728-3p
chr1
8866502
8866522
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC010642.2
chr19
58309727
58327248
-
AC012236.1
chr15
31221999
31230838
-
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC125807.2
chr12
3041437
3044950
+
AC245014.3
chr1
145281116
145281462
+
AC245033.4
chr15
82533175
82540008
-
AL022311.1
chr22
37876148
37895563
+
AL096870.2
chr14
24209646
24215987
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.