Entry Detail


General Information

Database ID:exR0514538
RNA Name:EEF1A1
RNA Type:mRNA
Chromosome:chr6
Starnd:-
Coordinate:
Start Site(bp):73515750End Site(bp):73523797
External Links:ENSG00000156508



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ADNP
chr20
50888916
50931437
-
AIF1L
chr9
131096476
131123152
+
AC008982.1
chr19
38817471
38840178
-
ADRM1
chr20
62302093
62308862
+
ALDH16A1
chr19
49453225
49471050
+
AGO2
chr8
140520156
140635633
-
ALDOA
chr16
30064164
30070457
+
ACIN1
chr14
23058564
23095614
-
ACAT1
chr11
108116695
108147603
+
ADA
chr20
44619522
44652233
-
AC073508.2
chr17
40627356
40665141
-
ABCF1
chr6
30571393
30597179
+
AKT2
chr19
40230317
40285536
-
ADORA2A
chr22
24417879
24442357
+
ACTB
chr7
5527148
5563784
-
ABRACL
chr6
139028745
139043302
+
AIDA
chr1
222668013
222713210
-
ACTR1A
chr10
102461881
102502712
-
ALDH9A1
chr1
165662216
165698863
-
ACTG1
chr17
81509971
81523847
-
AL035078.4
chr11
31812391
32104665
+
AC015813.2
chr17
57989038
58007246
-
ACACA
chr17
37084992
37406836
-
AC018523.2
chr11
14493783
14520344
-
ABHD2
chr15
89087459
89202355
+
ACAP1
chr17
7336529
7351477
+
AGL
chr1
99850361
99924023
+
AL121758.1
chr20
646626
675800
-
ACAA2
chr18
49782164
49813953
-
AC008763.3
chr19
7678501
7682854
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-21-5p
chr17
59841273
59841294
+
hsa-miR-142-3p
chr17
58331245
58331267
-
hsa-miR-155-5p
chr21
25573983
25574006
+
hsa-miR-3654
chr7
133034860
133034878
-
hsa-miR-6797-3p
chr19
41869675
41869696
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC004816.1
chr14
70809841
70815994
+
AC012236.1
chr15
31221999
31230838
-
AC015813.1
chr17
57989039
57994850
-
AC016876.2
chr17
7581964
7584086
-
AC019205.1
chr6
73263212
73301789
+
AC020663.1
chr16
4730115
4752565
-
AC023509.1
chr12
53441741
53467528
+
AC063949.2
chr12
92421531
92483680
+
AC092490.1
chr12
8788253
8795789
+
AC104461.1
chr1
200333193
200478669
+
AC132217.1
chr11
2129121
2129964
-
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL031058.1
chr6
7540451
7541338
-
AL035458.2
chr20
34234840
34281173
-
AL080317.2
chr6
111309203
111313517
+
AL121985.1
chr1
160670778
160699761
+
AL132780.1
chr14
22929607
22956374
+
AL137026.2
chr10
44259602
44261813
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.