Entry Detail


General Information

Database ID:exR0514541
RNA Name:EEF1D
RNA Type:mRNA
Chromosome:chr8
Starnd:-
Coordinate:
Start Site(bp):143579697End Site(bp):143599541
External Links:ENSG00000104529



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
ABCA2
chr9
137007234
137028922
-
ABCC5
chr3
183919934
184017939
-
ABHD10
chr3
111979010
111993368
+
AC012184.2
chr16
70299194
70372582
+
AC074143.1
chr16
67163385
67165815
+
AC090004.1
chr3
14135217
14148252
+
AC092143.1
chr16
89919165
89936092
+
AC092647.5
chr7
55887277
55955239
+
AC093525.2
chr16
2496032
2520218
+
AC244197.3
chrX
149477104
149540926
-
AC245033.1
chr15
82536788
82573194
-
ACLY
chr17
41866917
41930542
-
ACTA1
chr1
229431245
229434098
-
ACTB
chr7
5527148
5563784
-
ACTC1
chr15
34790230
34795549
-
ACTG1
chr17
81509971
81523847
-
ACTR3
chr2
113890063
113962596
+
ADGRE5
chr19
14380501
14408725
+
AFMID
chr17
78187317
78207701
+
AHCYL2
chr7
129225023
129430211
+
AL713999.1
chr1
155169409
155187272
-
ALDH9A1
chr1
165662216
165698863
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4517
chr16
28958587
28958611
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC067930.1
chr8
143579636
143580670
+
AC069281.2
chr7
100572232
100578700
-
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
AL132780.1
chr14
22929607
22956374
+
AL133166.1
chr14
29210986
29392048
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.