Entry Detail


General Information

Database ID:exR0514621
RNA Name:EIF3C
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):28688558End Site(bp):28735730
External Links:ENSG00000184110



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AARS2
chr6
44298731
44313347
-
ABCB9
chr12
122920951
122981649
-
AC005258.1
chr19
2269525
2341172
+
AC005943.1
chr19
1578339
1605445
-
AC010422.3
chr19
12643831
12648397
-
AC092143.1
chr16
89919165
89936092
+
AC110275.1
chr8
43018424
43077334
+
AC245033.1
chr15
82536788
82573194
-
ACBD4
chr17
45132600
45144181
+
ACER3
chr11
76860867
77026797
+
ACKR3
chr2
236567787
236582354
+
ACO2
chr22
41469117
41528989
+
ACTG1
chr17
81509971
81523847
-
ADD3
chr10
109996368
110135565
+
AFF4
chr5
132875395
132963634
-
AGPAT3
chr21
43865223
43987592
+
AIF1L
chr9
131096476
131123152
+
AL109827.1
chr20
35632340
35674544
-
ALDH7A1
chr5
126531200
126595362
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009022.1
chr16
69976297
70065948
-
AC010327.5
chr19
55216660
55221616
+
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC090204.1
chr8
32927913
33045445
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.