Entry Detail


General Information

Database ID:exR0514624
RNA Name:EIF3E
RNA Type:mRNA
Chromosome:chr8
Starnd:-
Coordinate:
Start Site(bp):108201216End Site(bp):108435333
External Links:ENSG00000104408



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABLIM1
chr10
114431113
114768061
-
AC008764.4
chr19
16577642
16660115
-
AC009133.6
chr16
29812261
29820092
+
AC012184.2
chr16
70299194
70372582
+
AC048338.1
chr12
122207779
122266423
-
AC079447.1
chr2
99141485
99322741
+
AC092587.1
chr2
99154998
99195298
+
AC104452.1
chr3
49416777
49429314
-
AC120057.2
chr17
7240427
7244635
-
ACTB
chr7
5527148
5563784
-
ADK
chr10
74151202
74709963
+
AHCY
chr20
34280268
34311802
-
AL136454.1
chr1
192716132
192716653
+
ALCAM
chr3
105366909
105576900
+
ALDH1B1
chr9
38392702
38398661
+
ALDH5A1
chr6
24494867
24537207
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-93-5p
chr7
100093815
100093837
-
hsa-miR-4284
chr7
73711327
73711344
+
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010618.3
chr19
17488990
17511889
-
AC021078.1
chr5
149494314
149504670
-
AC124312.5
chr15
25091786
25107469
-
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.