Entry Detail


General Information

Database ID:exR0514646
RNA Name:EIF4G2
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):10797050End Site(bp):10808940
External Links:ENSG00000110321



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASDHPPT
chr11
106075501
106098699
+
ABCC1
chr16
15949577
16143074
+
ABHD17B
chr9
71862452
71910931
-
ABHD8
chr19
17292131
17310236
-
ABI1
chr10
26746593
26861087
-
ABR
chr17
1003518
1229738
-
AC004922.1
chr7
99325879
99394653
+
AC005020.2
chr7
99558695
99607810
+
AC005324.4
chr17
15699692
15744778
+
AC018512.1
chr15
43772617
43799133
-
AC073896.1
chr12
56285916
56316059
-
AC120057.2
chr17
7240427
7244635
-
ACP1
chr2
264140
278283
+
ACTG1
chr17
81509971
81523847
-
ADSL
chr22
40346500
40390463
+
AFDN
chr6
167826922
167972023
+
AGPAT4
chr6
161129967
161274061
-
AKAP12
chr6
151239967
151358559
+
AKIRIN1
chr1
38991276
39006059
+
AL022238.4
chr22
40346529
40410054
+
AL590132.1
chr1
210858125
211134146
-
ALAD
chr9
113386312
113401290
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-92a-3p
chrX
134169544
134169565
-
hsa-miR-4485-3p
chr11
10508277
10508296
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004812.2
chr12
120116907
120119000
+
AC025279.1
chr16
29291220
29372110
+
AC087190.3
chr16
9104848
9113181
+
AC126365.1
chr17
20788071
20789584
+
AD000090.1
chr19
35557956
35581954
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.