Entry Detail


General Information

Database ID:exR0514648
RNA Name:EIF4H
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):74174245End Site(bp):74197101
External Links:ENSG00000106682



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCD4
chr14
74285269
74303055
-
ABCF2
chr7
151207837
151227166
-
AC010422.3
chr19
12643831
12648397
-
AC023055.1
chr12
55757275
55827546
-
AC046185.1
chr17
63702845
63752097
-
AC092647.5
chr7
55887277
55955239
+
AC139530.2
chr17
81703371
81720539
+
AC244197.3
chrX
149477104
149540926
-
ACBD6
chr1
180269653
180502954
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTN1
chr14
68874143
68979440
-
ACTN4
chr19
38647649
38731589
+
ADAMTSL4
chr1
150549369
150560937
+
ADD3
chr10
109996368
110135565
+
ADGRG2
chrX
18989307
19122637
-
ADIPOR1
chr1
202940826
202958572
-
ADRM1
chr20
62302093
62308862
+
AHI1
chr6
135283532
135497765
-
AHSA1
chr14
77457870
77469472
+
AKIRIN1
chr1
38991276
39006059
+
AL031708.1
chr16
1632259
1686715
+
AL109827.1
chr20
35632340
35674544
-
AL713999.1
chr1
155169409
155187272
-
ALDH7A1
chr5
126531200
126595362
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4444
chr2
177212768
177212785
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005618.1
chr5
141326210
141329357
+
AC007218.1
chr16
9666885
9676843
-
AC007878.1
chr2
71373938
71376320
+
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AC023509.1
chr12
53441741
53467528
+
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.