Entry Detail


General Information

Database ID:exR0514652
RNA Name:EIF5AL1
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):79512601End Site(bp):79516440
External Links:ENSG00000253626



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
AASS
chr7
122073549
122144255
-
AC005258.1
chr19
2269525
2341172
+
AC040162.1
chr16
67929614
67936017
-
AC073612.1
chr12
71674204
71698968
+
AC104452.1
chr3
49416777
49429314
-
AC118553.2
chr1
99970011
100083321
+
AC245033.1
chr15
82536788
82573194
-
ACADS
chr12
120725774
120740008
+
ACTB
chr7
5527148
5563784
-
ACTR1A
chr10
102461881
102502712
-
ADAR
chr1
154582057
154628013
-
AKR1A1
chr1
45550543
45570049
+
AKR1B1
chr7
134442356
134459284
-
AKT2
chr19
40230317
40285536
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AC109587.1
chr3
69013941
69056622
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.