Entry Detail


General Information

Database ID:exR0514719
RNA Name:ENO1
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):8861000End Site(bp):8879190
External Links:ENSG00000074800



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL049629.2
chr11
33698261
33722467
-
ACAD10
chr12
111686056
111757107
+
ACSS2
chr20
34872146
34927962
+
AC004832.3
chr22
30409255
30428990
+
AC048338.1
chr12
122207779
122266423
-
AGFG1
chr2
227472152
227561214
+
AHSA1
chr14
77457870
77469472
+
AC010422.5
chr19
12664828
12669397
-
AC010463.1
chr19
17267418
17282966
+
AKR1A1
chr1
45550543
45570049
+
AC011448.1
chr19
19516227
19536076
+
AHNAK
chr11
62433542
62556235
-
ACTG1
chr17
81509971
81523847
-
AL136295.5
chr14
24147548
24166452
+
AC091167.2
chr15
90249556
90272208
+
ALDH16A1
chr19
49453225
49471050
+
ACTA1
chr1
229431245
229434098
-
AC010422.3
chr19
12643831
12648397
-
AC073283.3
chr2
47065941
47176511
-
AL136454.1
chr1
192716132
192716653
+
ABRACL
chr6
139028745
139043302
+
ALDH18A1
chr10
95605941
95656711
-
ABCC1
chr16
15949577
16143074
+
AC138811.2
chr16
18788063
18801519
-
AC018523.2
chr11
14493783
14520344
-
AL033529.1
chr1
32465057
32600792
+
AC107871.1
chr15
68184032
68229718
-
ACIN1
chr14
23058564
23095614
-
AHCY
chr20
34280268
34311802
-
AAGAB
chr15
67200667
67255195
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-423-3p
chr17
30117131
30117153
+
hsa-miR-4426
chr1
192716333
192716349
+
hsa-miR-6728-3p
chr1
8866502
8866522
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC005261.3
chr19
57350848
57352012
-
AC005899.4
chr17
32328441
32329395
+
AC007952.4
chr17
19112000
19112636
-
AC008124.1
chr12
45718046
45727775
-
AC010655.2
chr7
128455937
128469197
+
AC010655.4
chr7
128455840
128493859
+
AC016876.2
chr17
7581964
7584086
-
AC021078.1
chr5
149494314
149504670
-
AC023509.1
chr12
53441741
53467528
+
AC026362.1
chr12
122975320
122982907
+
AC026401.3
chr16
15701237
15702118
+
AC079781.5
chr7
97851688
97972985
-
AC091057.1
chr15
30658717
30772993
+
AC091564.7
chr11
6610883
6616594
-
AC097478.1
chr4
89743792
89744305
+
AC109460.3
chr16
28974804
28990775
+
AC124068.2
chr15
89335053
89336161
+
AC132217.1
chr11
2129121
2129964
-
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL121832.2
chr20
62386303
62386970
-
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.